Phytoplankton
blooms are responsible for about 50% of photosynthesis on Earth and
therefore are important components of large biogeochemical cycles in the
ocean. Viruses that infect phytoplankton are also important since they
drive evolution within algal communities by manipulating the organic
material (proteins, lipids, sugars, DNA and others) of the phytoplankton
host for viral replication.
To better understand the molecular basis of these host–virus
interactions, the EU supported the project 'The role of cell signalling
and infochemicals in marine algal-virus interactions' (VIRUSIGNALLING).
Researchers studied the phytoplankton species Emiliania huxleyi and
its specific virus, EhV86. They looked at the chemical signals involved
in host–virus interactions with the aim of understanding how these
signals co-evolve in both species.
A major finding was that reactive oxygen species are central to the
signaling process involved in regulating cell fate and viral replication
cycles. In addition, viral replication depends on hijacking the host's
lipid metabolism, and increased fatty acid synthesis supports viral
assembly.
The gene products and metabolites specific to infection identified
by VIRUSIGNALLING scientists can now be used as novel biomarkers for
infection in oceans. This provides researchers with advanced new tools
to assess the ecology and biogeochemistry of phytoplankton host–virus
interactions.